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Table 4 GO enrichment analysis of MCODE network in PPI.MCODE algorithm was applied to this network, and GO enrichment analysis was applied to each MCODE network

From: Identification of hub genes in the subacute spinal cord injury in rats

Network

Shape

Gene

Go

Description

Log(q-value)

ALL

Ellipse

–

R-RNO-168249

Innate immune system

− 17.2

GO:0050778

positive regulation of immune response

− 15.4

GO:0002252

immune effector process

− 12.9

MCODE_1

Diamond

C3ar1 Ccl27 Pf4 S1pr3 Cxcl16 Hebp1 Gngt2 Anxa1 Gng13

R-RNO-418594

G alpha (i) signalling events

− 16.9

R-RNO-500792

GPCR ligand binding

− 15.5

R-RNO-388396

GPCR downstream signalling

− 14.7

MCODE_2

Rectangle

Itgb2 Cybb Cyba Vav1 Cd53 Cmtm6 Stk10

rno04670

Leukocyte transendothelial migration

− 7.2

ko04670

Leukocyte transendothelial migration

− 7.2

GO:0042554

superoxide anion generation

− 6.2

MCODE_3

Triangle

Shc1 Ptpn6 Inpp5d Lyn Cblb Lcp2

WP147

Kit receptor signaling pathway

− 11.4

R-RNO-512988

Interleukin-3, Interleukin-5 and GM-CSF signaling

− 9.8

R-RNO-21099

PECAM1 interactions

− 8.6

  1. PPI protein–protein interaction