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Fig. 2 | BMC Neuroscience

Fig. 2

From: A circular RNA derived from GLIS3 accelerates the proliferation of glioblastoma cells through competitively binding with miR-449c-5p to upregulate CAPG and GLIS3

Fig. 2

CircGLIS3 regulates CAPG and GLIS3 in GBM cells. A The expression levels of CAPG and GLIS3 in GBM tissue and normal deceased tissues were predicted from GEPIA database. B FISH was used to detect the co-localization of circGLIS3 and CAPG or GLIS3. C RIP assay accompanied with qRT-PCR analysis was carried out to investigate whether circGLIS3, CAPG, and GLIS3 were precipitated in the RISC. D QRT-PCR was performed to detect expression of CAPG and GLIS3 in GBM cells and NHAs with circGLIS3 knockdown. Student’s t-test was applied for statistical analysis in A/C while one-way ANOVA was applied for statistical analysis in D. *P < 0.05, **P < 0.01

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BMC Neuroscience

ISSN: 1471-2202

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