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Fig. 5 | BMC Neuroscience

Fig. 5

From: High-frequency repetitive transcranial magnetic stimulation (rTMS) protects against ischemic stroke by inhibiting M1 microglia polarization through let-7b-5p/HMGA2/NF-κB signaling pathway

Fig. 5

Let-7b-5p regulated HMGA2 expression in BV2 cells. a The predicted binding sites of let-7b-5p to 3′-UTR of HMGA2 gene. b Dual luciferase reporter assay of the relationship between let-7b-5p agomir and wild type 3′ UTR of HMGA2. c, d Western blots and quantification of HMGA2, p-IκBα, IκBα, p-P65 and P65 in BV2 cells with indicated treatment. n = 3. Data are expressed as mean ± SD; *P < 0.05, **P < 0.01 versus Ctrl group; #P < 0.05 versus OGD/R group

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BMC Neuroscience

ISSN: 1471-2202

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