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Fig. 1 | BMC Neuroscience

Fig. 1

From: Opposing actions of CRF-R1 and CB1 receptor on facial stimulation-induced MLI-PC plasticity in mouse cerebellar cortex

Fig. 1

Effect of CRF on 1 Hz facial stimulation-evokedMLI-PC LTD in vivo in mice. A Upper: Representative cell-attached recording traces showing air-puff stimulation (10 ms, 60 psi; arrows)-evoked responses in cerebellar PCs before (Pre) and after (post) delivering 1 Hz (240 pulses) facial stimulation during treatments with ACSF (control) and CRF (100 nM). B Summary of data showing the time course of normalized P1 amplitude before and after delivery of 1 Hz facial stimulation (arrow head) in ACSF (control, filled circle) and CRF (open circles). C Bar graph with individual data showing the normalized amplitude of P1 before (Pre), after (Post) delivery of 1 Hz stimulation. D Mean (± S.E.M.) with individual data showing the normalized pause of simple spike firing before (Pre), after (Post) delivery of 1 Hz stimulation. #P < 0.05 versus Pre of control; *P < 0.05 versus post of control. n = 7 mice in each group

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