Table 8 Demographic information and MRI scan parameters related to Alzheimer's Disease research projects
Study | Au et al. [49] | Li et al. [48] |
|---|---|---|
TR | 45 ms | – |
TR/TE | – | 41.8/3.3 ms |
Flip angle | 20\(^\circ \) | 20\(^\circ \) |
Bandwidth | – | 62.50 kHz |
FOV | 240 × 240 × 120 mm3 | 256 × 256 mm2 |
Matrix size | – | 256 × 256 |
Slice thickness | – | 1.0 mm |
Slice numbers | – | 124 |
TEs | 8 echoes, TE1: 4.0 ms /ΔTE: 5.2 ms | 16 echoes/TE spacing: 2.3 ms |
Total time | 5 min and 19 s | – |
Sequence | 3D fast-field echo\(FFE) | 3D multi gradient-echo (mGRE) |
Participants | 13 Patients with early stage AD, 10 Patients with late stage AD, and 30 healthy subjects | 22 Patients with AD, 22 Patients with MCI, 25 Patients with SCD, and 25 healthy subjects |
MRI scanner system | 3T MRI system (Philips Achieva TX, Best, The Netherlands) with an 8-channel head coil | 3T MRI system (Discovery MR 750, GE Healthcare, Milwaukee, WI) equipped with a 32-channel phased-array coil |
Study | Kim et al. [45] | Moon et al. [47] | Acosta-Cabronero et al. [44] |
|---|---|---|---|
TR | 43Â ms | Â | 35Â ms |
TR/TE | – | 37 ms/3.5 ms | – |
Flip angle | 20° | 20° | 17\(^\circ \) |
Bandwidth | – |  ± 41.67 kHZ | 50 Hz/pixel |
FOV | 220 × 198 mm2 | 240 × 240 mm2 |  |
Matrix size | – | 256 × 256 | 256 × 240 |
Slice Thickness | – | 2.5 mm | 2.0 mm |
slice Numbers | – | 56 | 72 |
TEs | TE1: 3.4/ΔTE: 6.0/ TE7: 39 ms | 8 echoes/ΔTE: 4.09 ms | 20 ms |
Total Time | – | 3 min and 32 s | 7 min |
Sequence | 3D fast field-echo (FFE) | Susceptibility-weighted angiography sequence [SWAN] | Susceptibility-weighted-imaging (SWI) |
Participants | 19 patients with aMCI, 19 patients with mild and probable AD, and 19 healthy subjects | 12 patients with VaD, 27 patients with AD, and 18 healthy subjects | 8 Patients with early-stage probable AD |
MRI scanner system | 3T MRI system (Achieva, Philips Medical Systems, Best, The Netherlands) | 3T MRI system (Signa HDxT; GE Medical Systems, Milwaukee, WI, USA) with an 8-channel head coil | 3T MRI system (Siemens Trio 3T superconductive magnet with gradient coils) |
Study | Cogswell et al. [8] | Gong [43] | Du et al. [5] |
|---|---|---|---|
TR | 28Â ms | 250Â ms | 22.9Â ms |
TR/TE | 40/49 ms | – | – |
Flip Angle | 15° | 35° | 12° |
Bandwidth | 25.6 kHz | – |  ± 31.25 Hz/pixel |
FOV | 200 × 200 mm2 | 19.2 \(\times \) 14.4 \(\times \) 9.6 cm3 | 25.6 × 25.6 cm2 |
Matrix size | 384 × 269 | – | 256 × 256 |
Slice thickness | 1.8 mm | – | 1.0 mm |
Slice numbers | 88 | – | – |
TEs | 6.7, 10.6, 14.5, 18.4, and 22.4 ms | TE1: 3.72//ΔTE: 5.52//TE10: 53.36 ms | 3.2 ms |
Total time | 6:37Â min | 90Â min | 4Â min and 24Â ms |
Sequence | 3D-MEGRE | Multi-echo, 3D gradient echo (mGRE) | 3D gradient-echo (GRE) |
Participants | 69 patients with MCI, 56 patients with amnestic dementia,and 296 healthy subjects | 4 Pairs of transgenic mice with abnormal beta amyloid-aggregation (Tg-SwDI) and wild type | 30 Patients with AD |
MRI scanner Sys##tem | 3T 3T MRI system (Siemens Prisma VE11C) | 7T MRI system (Bruker BioSpec 70/20USR, Billerica, MA) with an Avance III system | 3T MRI system (Discovery MR750 scanner; GE Medical Systems, USA) |