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Table 1 Mean intracranial pressure (ICP) values measured at baseline, day 1 and day 7

From: Intracranial pressure and optic disc changes in a rat model of obstructive hydrocephalus

Group

Baseline

ICP

mean ± SD

[min, max]

Day 1

ICP

mean ± SD

[min, max]

Day 7

ICP, mmHg

mean ± SD

[min, max]

Epidural,

mmHg

Epidural,

mmHg

Epidural,

mmHg

Epidural

after ventricular cannulation, mmHg

Ventricular, mmHg

Hydrocephalus

n = 8

3.17 ± 1.23

[1.76, 4.76]

15.49 ± 2.47

[11.28, 19.38]

****

4.74 ± 1.15

[3.33, 6.42]

4.81 ± 1.25

[3.34, 6.98]

4.82 ± 1.29

[3.11, 6.88]

Control

n = 4

2.26 ± 0.34

[1.98, 2.75]

5.81 ± 1.33

[4.32, 7.55]

4.06 ± 1.20

[3.05, 5.65]

4.01 ± 1.07

[2.95, 5.48]

2.83 ± 0.31

[2.08, 3.57]

  1. Obstructive hydrocephalus animals showed statistically significant elevations of the epidural ICP day 1 after kaolin injection compared to control animals. At day 7 the epidural ICP was measured before intraventricular cannulation and then simultaneously with the ventricular ICP to compare the two recording sites. Comparison ****p < 0.0001