Fig. 2

Diffusion tensor MRI on major white matter structures. a Fractional anisotropy (FA) map with highlighted 10 major white matter brain regions obtained by diffusion tensor imaging in a representative thyroxine (T4)-treated rat at PND10. Scaling of the FA map is between 0 and 0.7. b FA values in 10 different areas of the white matter in rat pups at PND10 following nine daily administrations of T4 (0.1 mg/kg, n = 6) or vehicle (water, n = 6). Data are presented as the mean ± SEM. Statistical significance is indicated as follows: **P < 0.01 (passed correction for the false discovery rate at q set at 0.1). fmi forceps minor of corpus callosum, gcc genu of corpus callosum, bcc body of corpus callosum, scc splenium of corpus callosum, fmj forceps major of corpus callosum, ec external capsule, aca anterior part of anterior commissure, ic internal capsule, opt optic tract, cp. cerebellar peduncle