Fig. 3

Euthyroid HT induces poor performance in Morris water maze in mice. a The average escape latency period for the mice to find the underwater platforms. Following a 5-day training session, the latency to find the escape platform was progressively shortened for both Con and HT mice, but the HT mice took a significantly longer time to find the escape platform compared to the control group at the 2nd to 5th training days. b No significant difference in swimming speed was seen between the two groups. c The representative path tracking of the Con and HT mice in orientation navigation tests. d, e The time spent on the platform and the number of crossing the platform in spatial probe tests. f The representative path of the Con and HT mice in spatial probe tests. Data are presented as the mean ± SEM; *p < 0.05, and **p < 0.01, vs. Con