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Fig. 5 | BMC Neuroscience

Fig. 5

From: Cellular distribution of C-C motif chemokine ligand 2 like immunoreactivities in frontal cortex and corpus callosum of normal and lipopolysaccharide treated animal

Fig. 5

CCL2-ir and GFAP or Iba-1 co-labeled somata in cortex and CC of LPS injected mice. A, B CCL2-ir positive rings/edges or cells (CCL2 panels, arrows), and GFAP labeled rings/edges or somata (GFAP panels, arrowheads) are observed; while, a CCL2-ir positive ring is regarded to lay inside of a GFAP labeled circles (A Merged panel, framed area and inset). Similarly, in the CC (B), a CCL2-ir ring is also laying against an edge formed by an astrocyte (B Merged panel, framed area and inset). Some CCL2-ir and GFAP co-labeled somata or processes are viewed in the CC (arrow-arrowheads). C, CCL2-ir positive (arrows) Iba-1 labeled hypertrophic somata (arrowheads) are presented in the cortex after systemic LPS (arrow-arrowheads). D, E More Iba-1 labeled amoeba like somata (arrowheads) in the CC are CCL2-ir positive (arrows) following systemic LPS (arrow-arrowheads in Merged panels). Scale bar = 50 µm in all A–E

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BMC Neuroscience

ISSN: 1471-2202

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