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Fig. 2 | BMC Neuroscience

Fig. 2

From: Does physical exercise improve or deteriorate treatment of multiple sclerosis with mitoxantrone? Experimental autoimmune encephalomyelitis study in rats

Fig. 2

Effect of exercise on the animal health, the EAE score and motor performance. A shows representative photographs of mitoxantrone treated rats on day 17 showing porphyrin spots near the eye of exercised and B sedentary rats, as well as C and D blue discoloration of their testes was noted. E represents the EAE score. Data were analyzed using Kruskal–Wallis Test, followed by Dunn's post hoc test and presented as median values with range, p < 0.05. The median values are presented as CNSED = 0, CNEX = 0, EAESED = 4, EAEEX = 4, MTSED = 1.5 and MTEX = 2.5. F shows the percentage to control of motor performance on day 17. Data were analyzed using one-way ANOVA followed by Tukey's Multiple Comparison Test and presented as mean ± S.D (p < 0.05). As compared with CNSED (*), CNEX ($), EAESED (#), EAEEX (%) and MTSED (&) groups. EAE experimental autoimmune encephalomyelitis; groups of CNSED sedentary control, CNEX exercised control, EAESED sedentary untreated EAE; EAEEX exercised untreated EAE; MTSED sedentary mitoxantrone, MTEX exercised mitoxantrone; (n = 6/group)

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BMC Neuroscience

ISSN: 1471-2202

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