Protein | Region | PDD/Ctrl | DLB/Ctrl | PDD/DLB |
---|
GFAP | SN | NS | NS | NS |
CP | NS | NS | ↑ (0.075) |
TC | ↑ (0.060) | ↑* (0.025) | NS |
Iba1 | SN | NS | NS | NS |
CP | NS | NS | NS |
TC | ↑* (0.020) | NS | NS |
LC3II | SN | NS | NS | NS |
CP | ↑ (0.074) | ↑* (0.040) | NS |
TC | NS | NS | NS |
p62 | SN | NS | NS | NS |
CP | NS | NS | NS |
TC | NS | NS | ↑ (0.052) |
Tom20 | SN | NS | NS | NS |
CP | NS | NS | NS |
TC | NS | NS | NS |
DRP1 | SN | NS | NS | NS |
CP | NS | NS | NS |
TC | NS | ↓ (0.066) | ↑* (0.016) |
MFN2 | SN | NS | NS | NS |
CP | ↑ (0.058) | NS | NS |
TC | NS | NS | NS |
- Statistical results from western blot results for mitochondrial, neuroinflammation and autophagy-related protein markers were investigated in this study. Western blot images were quantified using ImageJ, and the data were normalized to β-actin. The upwards arrow indicates an increase and the downwards arrow indicates a decrease. p < 0.1 was included in the bracket to show the trends of the protein levels. Kruskal–Wallis test was used to measure the differences between Control, PDD, and DLB samples
- NS no significance
- *p < 0.05