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Table 4 Statistic results of mitochondrial, neuroinflammation, and autophagy-related protein markers tested in three regions of Control (Ctrl), PDD, and DLB post-mortem samples

From: Increased expression of pathological markers in Parkinson’s disease dementia post-mortem brains compared to dementia with Lewy bodies

Protein

Region

PDD/Ctrl

DLB/Ctrl

PDD/DLB

GFAP

SN

NS

NS

NS

CP

NS

NS

↑ (0.075)

TC

↑ (0.060)

↑* (0.025)

NS

Iba1

SN

NS

NS

NS

CP

NS

NS

NS

TC

↑* (0.020)

NS

NS

LC3II

SN

NS

NS

NS

CP

↑ (0.074)

↑* (0.040)

NS

TC

NS

NS

NS

p62

SN

NS

NS

NS

CP

NS

NS

NS

TC

NS

NS

↑ (0.052)

Tom20

SN

NS

NS

NS

CP

NS

NS

NS

TC

NS

NS

NS

DRP1

SN

NS

NS

NS

CP

NS

NS

NS

TC

NS

↓ (0.066)

↑* (0.016)

MFN2

SN

NS

NS

NS

CP

↑ (0.058)

NS

NS

TC

NS

NS

NS

  1. Statistical results from western blot results for mitochondrial, neuroinflammation and autophagy-related protein markers were investigated in this study. Western blot images were quantified using ImageJ, and the data were normalized to β-actin. The upwards arrow indicates an increase and the downwards arrow indicates a decrease. p  < 0.1 was included in the bracket to show the trends of the protein levels. Kruskal–Wallis test was used to measure the differences between Control, PDD, and DLB samples
  2. NS no significance
  3. *p  < 0.05