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Table 3 Statistic results of PD-related protein markers tested in three regions of Control (Ctrl), PDD, and DLB post-mortem samples

From: Increased expression of pathological markers in Parkinson’s disease dementia post-mortem brains compared to dementia with Lewy bodies

Protein

Region

PDD/Ctrl

DLB/Ctrl

PDD/DLB

TH

SN

NS

NS

NS

CP

↓* (0.021)

↓** (0.003)

NS

TC

↑ (0.096)

↑* (0.038)

NS

DAT

SN

NS

NS

NS

CP

NS

NS

NS

TC

↑ (0.051)

NS

NS

α-Syn

SN

NS

NS

NS

CP

↑* (0.049)

↑ (0.065)

NS

TC

NS

NS

NS

p-α-SynS129

SN

NS

NS

NS

CP

NS

NS

NS

TC

NS

NS

NS

DD2R

SN

NS

NS

NS

CP

NS

NS

NS

TC

↑* (0.024)

NS

↑* (0.043)

  1. Statistical results from western blot results for PD-related protein markers tested in this study. Western blot images were quantified using ImageJ, and the data were normalized to β-actin. The upwards arrow indicates an increase and the downwards arrow indicates a decrease. p  < 0.1 was included in the bracket to show the trends of the protein levels. Kruskal–Wallis test was used to measure the differences between Control, PDD, and DLB samples
  2. NS no significance
  3. *p  < 0.05 and **p  < 0.01