Fig. 3

Increased neuroinflammation, mitophagy activity, and mitochondrial dynamics in PDD. a Multivariate analysis of post-mortem samples from TC by western blot. Twenty micrograms of protein were used per well for SDS-PAGE. Blots were cropped from different gels. Representative western blot images were shown. Statistical results of the relative protein levels of GFAP (b), IBA1 (c), and DRP1 (d). e Multivariate analysis of post-mortem samples from CP by western blot. Blots were cropped from different gels. Representative western blot images were shown. All blot images with significant changes were included in the Additional file 1: Fig. S3. Statistical results of the relative protein levels of LC3II (f), and MFN2 (g). Protein values are normalized to β-actin levels and control samples. Data are presented as the mean  ±  SEM. Kruskal–Wallis test was used to measure the differences between Control, PDD, and DLB samples. *p  < 0.05. Sample numbers, Control  = 9, PDD  =  10, and DLB  = 9