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Fig. 2 | BMC Neuroscience

Fig. 2

From: An ontogenic study of receptor mechanisms by which acute administration of low-doses of methamphetamine suppresses DOI-induced 5-HT2A-receptor mediated head-twitch response in mice

Fig. 2

ae show different regions of the PFC sections of the vehicle + DOI treated mice brain at 5 coronal levels (− 2.68 mm, − 2.34 mm, − 2.1 mm, − 1.9 mm, and − 1.7 mm relative to bregma Paxinos and Franklin [38]), in which c-fos numbers were counted, scale bars = 500 μm (ae). Illustrations are adapted from the atlas of Paxinos and Franklin [38]. c-fos immunoreactivity was counted when the cell nucleus was round or oval, completely filled and double-labeled with DAPI, scale bars = 10 μm (fh). Abbreviations: AI: agranular insular cortex; Cg1: cingulate cortex area 1; DLO: dorsal lateral orbital cortex; DP: dorsal peduncular cortex; FrA: frontal associated cortex; IL: infralimbic cortex; LO: lateral orbital cortex; M1: primary motor cortex; M2: secondary motor cortex; MO: medial orbital cortex; PrL: prelimbic cortex, S1: primary somatosensory area; VO: ventral orbital cortex

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