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Fig. 4 | BMC Neuroscience

Fig. 4

From: Metformin attenuates sepsis-induced neuronal injury and cognitive impairment

Fig. 4

Metformin alleviates CLP-induced cognitive impairment. A Experimental design sketch. The open field results showed no significant difference in the total distance covered (B). Novel object recognition test (NOR) showed the measured recognition index of the new object at 2 h (C) and 24 h (D). Morris water maze (MWM) result showed the latency to find the hidden platform (E). On day 6, the platform was removed, and the time spent in the target quadrant (F), and the number of target platform crossing (G) were evaluated. n  = 10. p value significance is calculated from a one-way ANOVA or two-way ANOVA tests, all data represent mean  ±  SEM. *p  < 0.05, **p  < 0.01vs CLP group

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