Fig. 2
From: Metformin attenuates LPS-induced neuronal injury and cognitive impairments by blocking NF-κB pathway
LPS treatment induces synaptic dysfunction in rats. A, B Hippocampal CA3-CA1 LTP and its quantification (A) were recorded using the MED64 system. Normalized CA3-CA1 fEPSP mean slope recorded from the CA1 dendritic region in hippocampal slices (B). C, D Brain tissues from hippocampi were homogenized, and synaptic protein levels were detected by immunoblotting. n = 3. p value significance is calculated from a T-test, and data are presented as mean ± SEM. *p < 0.05, **p < 0.01 vs control group