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Fig. 1 | BMC Neuroscience

Fig. 1

From: Effect of increased positive end-expiratory pressure on intracranial pressure and cerebral oxygenation: impact of respiratory mechanics and hypovolemia

Fig. 1

The impacts of positive end-expiratory pressure in animals with normovolemia and normal intracranial pressure (Series I, n = 10 per group): Data were presented as mean and standard deviation. RM-ANOVA was used. The corresponding changes of mean arterial pressure were presented in grey lines (showing means only), solid line: control group, dash line: chest wall strapping group. A ICP significantly increased when PEEP was increased (p < 0.001 for both groups), and the magnitude was significantly higher in the chest wall strapping group than in the control group (p = 0.014). B PtiO2 significantly decreased when PEEP was increased (p < 0.001 for both groups), but the magnitude was similar between groups (p = 0.927). C CO significantly decreased with PEEP increment (p < 0.001 for both groups), while no difference was observed between groups (p = 0.907). D CPP significantly decreased with PEEP increment (p < 0.001 for both groups), no difference was observed between groups (p = 0.645). ICP intracranial pressure, PEEP positive end-expiratory pressure, PtiO2 brain tissue O2 tension, CO cardiac output, CPP cerebral perfusion pressure

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