Fig. 1

The structure of brain microcirculatory mainstream of the rats from control group after traumatic brain injury. (a Arteriole. One day after the TBI vascular fullness, single perivascular hemorrhages, aggregates of erythrocytes were observed and perivascular edema was highly expressed, b—Venule. One day after the TBI, diapedesis, stored erythrocytes were observed and as well as highly expressed perivascular edema, c—Capillary. One day after the TBI in brain spawn capillaries the erythrocytes were absent. In some capillaries they were like sludges. Also everywhere there was highly expressed perivascular edema, d—Arteriole. 3 days after the TBI in arterioles clearance there were pink hyaline thrombuses, highly expressed perivascular edema was formed, e—Venule. 3 days after the TBI sludge erythrocytes and hyaline like masses, highly expressed endothelium edema and prevascular edema were noted in venules clearances, f—Capillary. 3 days after the TBI sludge erythrocytes, endothelium edema, highly expressed perivascular edema were noticed in the clearance, g—Arteriole. 7 days after the TBI in arterioles there were the parietal erythrocytes aggregations. Moderate endothelium edema was observed and perivascular edema was highly expressed, h—Venule. 7 days after the TBI in venules there was moderate endothelium edema, in the clearance between them there were protein masses, slagged of erythrocytes and blood clots of erythrocytes, moderately expressed perivascular edema was defined everywhere, i—Capillary. 7 days after the TBI in capillaries plethora, highly expressed endothelium and perivascular edema were noted, j—Arteriole. 12 days after the TBI in arteriole lumen there were erythrocytes and moderate perivascular edema, k—Venule. 12 days after the TBI free laying erythrocytes, endothelium edema was not expressed, moderately expressed perivascular edema was defined were defined, l—Capillary. 12 days after the TBI in the capillary lumen there were free laying erythrocytes, moderate endothelium edema and moderate perivascular edema). Scale bar is 100 μm, original magnification × 200 for arteriole and venule. Scale bar is 50 μm, original magnification × 400 for capillary. Abbreviations: Ag—aggregates from red blood cells, Ed edema, En endothelium, H—hyaline blood clots, RBC—red blood cells, T thrombuses