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Table 2 Scoring of histological findings of pigs uninfected and infected with S. suis serotype 2

From: In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

Age of infected pigs (wk) Total no. of pigs Sex (f/m) S. suis strain No. of pigs/Total no. of pigs ɷe
Brain Serosa Spleen and liver Lung
Meningitis, choroiditis Pleuritis or peritonitis Splenitisa or hepatitis Pneumonia
5b 3c 1d 4b 2c 1d 4b 2c 1d 4b 2c 1d
7–8 6 (3/3) Uninfected 0/6 0/6 0/6 1/6 0/6 0/6 0/6 0/6 0/6 1/6 0/6 0/6 0.66
7–8 6 (1/5) 10 1/6 1/6* 0/6 0/6 0/6 0/6 0/6 2/6 0/6 1/6 0/6 0/6 1.17
  1. *Minimally focal/multifocal lymphoplasmacellular Plexus chorioiditis (not in score)
  2. aNeutrophilic accumulation in the splenic red pulp
  3. bScoring of 4 and 5 indicates moderate to severe diffuse or multifocal fibrinosuppurative inflammations
  4. cScoring of 2 and 3 indicates mild focal fibrinosuppurative inflammation
  5. dIndividual single perivascular neutrophils received a score of 1
  6. eω = ∑scoremax / nanimals[50]
  7. wk = weeks; f = female; m = male