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Fig. 2 | BMC Neuroscience

Fig. 2

From: Brain size reductions associated with endothelin B receptor mutation, a cause of Hirschsprung’s disease

Fig. 2

ETB−/− rat has a grossly normal intracranial morphology. A, and B represented respective parasagittal micro-CT views of intracranial morphology and isolated brain of sl/sl (ETB−/−) rat. A demonstrated the presence of major craniofacial features and neural structures as labelled. B illustrated magnified micro-CT view of the ETB−/− brain with additional details, which were also presented in the micro-CT scans of wildtype (ETB+/+) rat, C. Lastly, H&E micrograph of the micro-CT scanned sl/sl rat brain confirmed the presence of the identified structures, D. The anatomical features identified were labelled as follows: Acb  accumbens nucleus, AO  anterior olfactory bulb, apons  anterior pons, CA1  CA1 field of hippocampus, CA3  CA3 field of hippocampus, CER  cerebellum, Cpu  caudate putamen, FrCtx  frontal cortex, Hypo  hypothalamus, IC  inferior colliculus, med  medulla, Pit  pituitary gland, PTh  posterior thalamus, SC  superior colliculus, Th  thalamus, U. Inc  upper incisor, Tong  tongue, Trac  trachea, Epi  epiglottis, H. b  hyoid bone, H. palate  hard palate, L. Inc  lower incisor, NasCa  nasal cavity, Nasop  nasopharynx, Orop  oropharynx

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