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Fig. 3 | BMC Neuroscience

Fig. 3

From: MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease

Fig. 3

Testing social interaction and social memory using the three-chamber test. SB-3CT and vehicle-treated E4FAD mice were tested for A, B social interaction (one mouse vs empty cage) and C, D social memory (novel mouse vs familiar mouse) in the three-chamber test. Time spent in A, C the whole chamber containing the mouse/empty cage and B, D the proximal zone surrounding the cages was measured (areas shown in green in each accompanying schematic). Animals were approximately 5 months of age and values represent mean ± SEM (N = 14, 5 males, 9 females for each group). No statistical significance was identified in any measures by ANOVA. E4FAD Apolipoprotein E4 x Familial Alzheimer’s disease, SEM Standard error of the mean, ANOVA Analysis of variance

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