Skip to main content
Fig. 2 | BMC Neuroscience

Fig. 2

From: Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism

Fig. 2

Social novelty preference behavior of wild-type (WT, blue) and Chd8+/∆SL (Chd8+/−, red) mice in the three-chamber test. In the sociability phase, bars indicate time spent in the left chamber with a social target (stranger 1), while in the empty center chamber and right chamber with a non-social target for male (a) and female (b) mice. c The ratio for novelty in sociability phase (time with stranger 1/non-social object). In the social preference phase, bars indicate time spent in the left chamber with a familiar mouse (stranger 1), while in the empty center chamber and left chamber with a new mouse (Stranger 2) for male (d) and female (e) mice. f The ratio for novelty (time with Stranger 2 / time with Stranger 1). Columns with different superscript letters (a, b) are significantly different at p < 0.05

Back to article page