Skip to main content

Table 1 demographic and clinical feature of female and male PD within the same genetic group

From: Sex effects on clinical features in LRRK2 G2385R carriers and non-carriers in Parkinson's disease

  LRRK2 G2385R carriers (N = 79) LRRK2 G2385R non-carriers (N = 534)
  Female (N = 37) Male (N = 42) P Female (N = 239) Male (N = 295) P
Age 61.3 (11.6) 64.7 (7.5) 0.497 61.5 (10.9) 61.5 (10.3) 0.990
Disease duration 5.2 (3.1) 5.4 (4.1) 0.807 5.0 (4.1) 5.1 (4.5) 0.858
AAO 57.4 (11.8) 59.6 (8.1) 0.342 56.1 (11.2) 56.0 (10.5) 0.900
H-Y stage 1.7 (0.5) 1.8 (0.6) 0.565 1.9 (0.7) 1.9 (0.7) 0.874
MDS-UPDRS II 8.8 (5.5) 10.7 (7.1) 0.189 8.7 (7.3) 9.9 (7.8) 0.063
MDS-UPDRS III 24.7 (18.7) 24.6 (15.9) 0.968 22.1 (17.8) 25.0 (19.2) 0.080
NMSS 24.2 (30.0) 30.6 (32.0) 0.359 28.7 (30.7) 31.0 (33.3) 0.414
MOCA 21.7 (6.9) 24.7 (4.2) 0.046 22.5 (5.3) 23.0 (4.9) 0.398
PDSS 96.5 (49.1) 109.7 (44.1) 0.216 100.7 (46.0) 105.8 (43.0) 0.186
HAMD 5.1 (4.6) 4.3 (3.9) 0.384 5.8 (5.3) 5.3 (5.2) 0.288
HARS 5.2 (5.9) 6.5 (5.1) 0.270 7.2 (6.3) 6.2 (6.4) 0.061
SS-16 5.8 (4.0) 6.8 (3.8) 0.270 6.2 (4.2) 5.8 (3.8) 0.265
RBD-HK 15.2 (16.4) 14.1 (16.5) 0.753 13.7 (16.1) 14.0 (18.3) 0.821
SCOPA-AUT 6.9 (8.7) 9.4 (8.5) 0.192 8.7 (9.0) 10.2 (9.1) 0.055
ESS 5.1 (5.5) 5.8 (5.9) 0.574 4.8 (5.3) 6.6 (6.2)  < 0.001
PDQ-39 13.8 (15.5) 16.7 (18.5) 0.462 18.0 (18.8) 15.9 (17.2) 0.192
SN +  37.5% 38.5% 1.000 28.8% 45.3% 0.031