Table 1 demographic and clinical feature of female and male PD within the same genetic group
From: Sex effects on clinical features in LRRK2 G2385R carriers and non-carriers in Parkinson's disease
|  | LRRK2 G2385R carriers (N = 79) | LRRK2 G2385R non-carriers (N = 534) | ||||
|---|---|---|---|---|---|---|
|  | Female (N = 37) | Male (N = 42) | P | Female (N = 239) | Male (N = 295) | P |
Age | 61.3 (11.6) | 64.7 (7.5) | 0.497 | 61.5 (10.9) | 61.5 (10.3) | 0.990 |
Disease duration | 5.2 (3.1) | 5.4 (4.1) | 0.807 | 5.0 (4.1) | 5.1 (4.5) | 0.858 |
AAO | 57.4 (11.8) | 59.6 (8.1) | 0.342 | 56.1 (11.2) | 56.0 (10.5) | 0.900 |
H-Y stage | 1.7 (0.5) | 1.8 (0.6) | 0.565 | 1.9 (0.7) | 1.9 (0.7) | 0.874 |
MDS-UPDRS II | 8.8 (5.5) | 10.7 (7.1) | 0.189 | 8.7 (7.3) | 9.9 (7.8) | 0.063 |
MDS-UPDRS III | 24.7 (18.7) | 24.6 (15.9) | 0.968 | 22.1 (17.8) | 25.0 (19.2) | 0.080 |
NMSS | 24.2 (30.0) | 30.6 (32.0) | 0.359 | 28.7 (30.7) | 31.0 (33.3) | 0.414 |
MOCA | 21.7 (6.9) | 24.7 (4.2) | 0.046 | 22.5 (5.3) | 23.0 (4.9) | 0.398 |
PDSS | 96.5 (49.1) | 109.7 (44.1) | 0.216 | 100.7 (46.0) | 105.8 (43.0) | 0.186 |
HAMD | 5.1 (4.6) | 4.3 (3.9) | 0.384 | 5.8 (5.3) | 5.3 (5.2) | 0.288 |
HARS | 5.2 (5.9) | 6.5 (5.1) | 0.270 | 7.2 (6.3) | 6.2 (6.4) | 0.061 |
SS-16 | 5.8 (4.0) | 6.8 (3.8) | 0.270 | 6.2 (4.2) | 5.8 (3.8) | 0.265 |
RBD-HK | 15.2 (16.4) | 14.1 (16.5) | 0.753 | 13.7 (16.1) | 14.0 (18.3) | 0.821 |
SCOPA-AUT | 6.9 (8.7) | 9.4 (8.5) | 0.192 | 8.7 (9.0) | 10.2 (9.1) | 0.055 |
ESS | 5.1 (5.5) | 5.8 (5.9) | 0.574 | 4.8 (5.3) | 6.6 (6.2) |  < 0.001 |
PDQ-39 | 13.8 (15.5) | 16.7 (18.5) | 0.462 | 18.0 (18.8) | 15.9 (17.2) | 0.192 |
SN +  | 37.5% | 38.5% | 1.000 | 28.8% | 45.3% | 0.031 |