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Fig. 6 | BMC Neuroscience

Fig. 6

From: Behavioral sensitization induced by methamphetamine causes differential alterations in gene expression and histone acetylation of the prefrontal cortex in rats

Fig. 6

Validation of changes in the mRNA expression and H3/H4 histone acetylation of ANP32A (a, b) and POU3F2 (c, d). The results of real-time PCR and ChIP-PCR analyses revealed the changes in ANP32A and POU3F2 expression in the different phases of METH-induced behavioral sensitization. Data are presented as the means ± SEM, n = 9–10 rats per group for the ANP32A analysis and 14 rats per group for the POU3F2 analysis. *P < 0.05, **P < 0.01, one-way ANOVA followed by Tukey’s post hoc test for the challenge test and t-test for the development or withdrawal test

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