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Table 3 ABR thresholds in Nav1.9+/+, −/− mice at different age

From: SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves

Age (day)

8 K

16 K

WT

Nav1.9−/−

WT

Nav1.9−/−

P21

38.7 ± 5.5

39.3 ± 5.3

30.0 ± 8.5

44.3 ± 8.9**

P30

37.5 ± 6.5

36.9 ± 13.3

40.0 ± 9.1

72.9 ± 17.5*

P60

39.0 ± 8.1

36.7 ± 6.6

41.7 ± 6.6

78.9 ± 10.5***

  1. Asterisks indicate significant differences (*p < 0.05, **p < 0.01, ***p < 0.001) as compared with WT group
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BMC Neuroscience

ISSN: 1471-2202

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