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Table 3 ABR thresholds in Nav1.9+/+, −/− mice at different age

From: SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves

Age (day) 8 K 16 K
WT Nav1.9−/− WT Nav1.9−/−
P21 38.7 ± 5.5 39.3 ± 5.3 30.0 ± 8.5 44.3 ± 8.9**
P30 37.5 ± 6.5 36.9 ± 13.3 40.0 ± 9.1 72.9 ± 17.5*
P60 39.0 ± 8.1 36.7 ± 6.6 41.7 ± 6.6 78.9 ± 10.5***
  1. Asterisks indicate significant differences (*p < 0.05, **p < 0.01, ***p < 0.001) as compared with WT group