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Table 2 ABR thresholds in Nav1.9+/+ (WT), +/−, −/− mice at 2 months of age

From: SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves

Group Frequency (kHz)
2 8 12 16
Nav1.9+/+ 57.5 ± 9.9 39.0 ± 8.1 41.0 ± 11.4** 41.7 ± 6.6***
Nav1.9+/− 70.0 ± 7.1 42.5 ± 15.5 42.5 ± 15.0** 58.8 ± 14.9*
Nav1.9−/− 70.0 ± 11.5 36.7 ± 6.6 79.3 ± 13.7 78.9 ± 10.5
  1. Asterisks indicate significant differences (*p < 0.05, **p < 0.01, ***p < 0.001) as compared with the Nav1.9−/− group