Characteristics | Q1 | Q2 | Q3 | Q4 | p value |
---|---|---|---|---|---|
No. of patients | 125 | 135 | 130 | 131 | |
Age, years, mean (SD) | 72.54 (13.50) | 70.09 (12.48) | 67.58 (12.64) | 67.59 (13.96) | 0.006 |
Female, (%) | 64 (51.20%) | 69 (51.11%) | 50 (38.46%) | 49 (37.40%) | 0.026 |
Hypertension, (%) | 113 (90.40%) | 109 (80.74%) | 113 (86.92%) | 110 (83.97%) | 0.150 |
Diabetes, % | 34 (27.20%) | 31 (22.96%) | 34 (26.15%) | 28 (21.37%) | 0.671 |
Hyperlipidemia, % | 36 (28.80%) | 53 (39.26%) | 55 (42.31%) | 65 (49.62%) | 0.008 |
Previous stroke, % | 26 (20.80%) | 28 (20.74%) | 21 (16.15%) | 21 (16.03%) | 0.594 |
Coronary heart disease, % | 16 (12.80%) | 10 (7.41%) | 14 (10.77%) | 11 (8.40%) | 0.461 |
Atrial fibrillation, % | 26 (20.80%) | 25 (18.52%) | 19 (14.62%) | 16 (12.21%) | 0.245 |
Current cigarette smoking, % | 14 (11.20%) | 8 (5.93%) | 19 (14.62%) | 13 (9.92%) | 0.138 |
NIHSS, median (IQR) | 4 (2–8) | 4 (2–6) | 3 (1–6) | 2 (1–6) | 0.005 |
Premorbid mRS score, median (IQR) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0.293 |
Stroke subtypes | 0.006 | ||||
Large artery atherosclerosis | 40 (32.00%) | 61 (45.19%) | 48 (36.92%) | 39 (29.77%) | |
Cardioembolic stroke | 21 (16.80%) | 22 (16.30%) | 17 (13.08%) | 17 (12.98%) | |
Small artery disease | 59 (47.20%) | 52 (38.52%) | 64 (49.23%) | 75 (57.25%) | |
Other etiology/unknown | 5 (4.00%) | 0 (0.00%) | 1 (0.77%) | 0 (0.00%) | |
IV rtPA, % | 7 (5.60%) | 13 (9.63%) | 9 (6.92%) | 16 (12.21%) | 0.237 |
Proton pump inhibitors, % | 56 (44.80%) | 54 (40.00%) | 59 (45.38%) | 44 (33.59%) | 0.186 |
Triglyceride, mmol/L, median (IQR) | 1.20 (0.89–1.60) | 1.38 (1.00–1.82) | 1.40 (0.94–1.92) | 1.52 (1.06–2.38) | 0.005 |
Total cholesterol, mmol/L, mean (SD) | 4.77 (1.06) | 4.99 (1.18) | 4.92 (1.37) | 5.00 (1.04) | 0.364 |
High-density lipoprotein cholesterol, mmol/L, mean (SD) | 1.36 (0.35) | 1.34 (0.39) | 1.28 (0.37) | 1.24 (0.37) | 0.035 |
Low-density lipoprotein cholesterol, mmol/L, mean (SD) | 2.37 (0.70) | 2.52 (0.74) | 2.48 (0.82) | 2.53 (0.70) | 0.290 |
EMR, median (IQR) | 0.04 (0.01–0.05) | 0.12 (0.10–0.15) | 0.26 (0.21–0.30) | 0.49 (0.40–0.76) | < 0.001 |
Poor outcome | 65 (52.00%) | 53 (39.26%) | 34 (26.15%) | 29 (22.14%) | < 0.001 |