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Table 1 Baseline characteristics of study participants according to quartiles of eosinophil-to-monocyte ratio (EMR)

From: Eosinophil-to-monocyte ratio is a potential biomarker in the prediction of functional outcome among patients with acute ischemic stroke

Characteristics

Q1

Q2

Q3

Q4

p value

No. of patients

125

135

130

131

 

Age, years, mean (SD)

72.54 (13.50)

70.09 (12.48)

67.58 (12.64)

67.59 (13.96)

0.006

Female, (%)

64 (51.20%)

69 (51.11%)

50 (38.46%)

49 (37.40%)

0.026

Hypertension, (%)

113 (90.40%)

109 (80.74%)

113 (86.92%)

110 (83.97%)

0.150

Diabetes, %

34 (27.20%)

31 (22.96%)

34 (26.15%)

28 (21.37%)

0.671

Hyperlipidemia, %

36 (28.80%)

53 (39.26%)

55 (42.31%)

65 (49.62%)

0.008

Previous stroke, %

26 (20.80%)

28 (20.74%)

21 (16.15%)

21 (16.03%)

0.594

Coronary heart disease, %

16 (12.80%)

10 (7.41%)

14 (10.77%)

11 (8.40%)

0.461

Atrial fibrillation, %

26 (20.80%)

25 (18.52%)

19 (14.62%)

16 (12.21%)

0.245

Current cigarette smoking, %

14 (11.20%)

8 (5.93%)

19 (14.62%)

13 (9.92%)

0.138

NIHSS, median (IQR)

4 (2–8)

4 (2–6)

3 (1–6)

2 (1–6)

0.005

Premorbid mRS score, median (IQR)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0.293

Stroke subtypes

0.006

 Large artery atherosclerosis

40 (32.00%)

61 (45.19%)

48 (36.92%)

39 (29.77%)

 

 Cardioembolic stroke

21 (16.80%)

22 (16.30%)

17 (13.08%)

17 (12.98%)

 

 Small artery disease

59 (47.20%)

52 (38.52%)

64 (49.23%)

75 (57.25%)

 

 Other etiology/unknown

5 (4.00%)

0 (0.00%)

1 (0.77%)

0 (0.00%)

 

IV rtPA, %

7 (5.60%)

13 (9.63%)

9 (6.92%)

16 (12.21%)

0.237

Proton pump inhibitors, %

56 (44.80%)

54 (40.00%)

59 (45.38%)

44 (33.59%)

0.186

Triglyceride, mmol/L, median (IQR)

1.20 (0.89–1.60)

1.38 (1.00–1.82)

1.40 (0.94–1.92)

1.52 (1.06–2.38)

0.005

Total cholesterol, mmol/L, mean (SD)

4.77 (1.06)

4.99 (1.18)

4.92 (1.37)

5.00 (1.04)

0.364

High-density lipoprotein cholesterol, mmol/L, mean (SD)

1.36 (0.35)

1.34 (0.39)

1.28 (0.37)

1.24 (0.37)

0.035

Low-density lipoprotein cholesterol, mmol/L, mean (SD)

2.37 (0.70)

2.52 (0.74)

2.48 (0.82)

2.53 (0.70)

0.290

EMR, median (IQR)

0.04 (0.01–0.05)

0.12 (0.10–0.15)

0.26 (0.21–0.30)

0.49 (0.40–0.76)

< 0.001

Poor outcome

65 (52.00%)

53 (39.26%)

34 (26.15%)

29 (22.14%)

< 0.001

  1. EMR eosinophil-to-monocyte ratio, IQR interquartile range, IV rtPA intravenous recombinant tissue plasminogen activator, NIHSS National Institutes of Health Stroke Scale