Cytokine/chemokine | [Saliva]/[plasma] | [Plasma]/[CSF] | ||||
---|---|---|---|---|---|---|
Patients | Healthy controls | Relative to controls | Patients | Healthy controls | Relative to controls | |
IL-17D | 4.57(0.95–8.71) | 3.59 (0.92–6.48) | ↑ | 0.07 (0.02–0.16) | 0.10 (0.03–0.54) | ↓ |
IL-17F | 0.28 (0.02–0.76) | 0.19 (0.04–0.77) | ↑ | 14.72 (4.21–46.64) | 21.24 (6.06–65.60) | ↓ |
IL-3 | 3.74 (0.56-12-98) | 3.06 (0.53- | ↑ | 2.86 (0.39–19.03) | 2.33 (0.36–8.99) | ↑ |
IL-17E-IL-25 | 0.31 (0.09–0.59) | 0.29 (0.01–1.53) | ↑ | 25.74 (4.09-150.27) | 40.80 (1.89-150.29) | ↓ |
IL-31 | 0.24 (0.05–0.40) | 0.25 (0.07–0.53) | ↓ | 9.11 (2.86–21.59) | 9.68 (1.86–17.31) | ↓ |
IL-17B | 7.27 (1.53–12.97) | 6.84 (0.89–12.45) | ↑ | 0.31 (0.11–1.68) | 0.32 (0.06–0.98) | ↓ |
IL-23 | 0.38 (0.02–2.73) | 0.71 (0.04-7.00) | ↓ | 92.23 (7.1-1027.13) | 40.72 (3.43–110.70) | ↑ |
IL-33 | 0.96 (0.34–2.30) | 0.95 (0.20-0.3.06) | ↑ | 2.57 (0.7-11.92) | 2.59 (0.42–7.01) | ↓ |
ENA-78 | 1.61 (0.06–12.87) | 3.01 (0.01–29.21) | ↓ | 38.11 (4.2-141.85) | 87.81 (2.98–327.60) | ↓ |
VEGF-A | 72.43 (15.60-183.01) | 40.97 (5.52–76.75) | ↑ | 8.82 (3.95–21.58) | 15.53 (4.59–77.95) | ↓ |
IL-7 | 1.77 (0.59–5.08) | 2.26 (0.38–6.11) | ↓ | 4.58 (1.16–9.13) | 6.21 (1.49–13.35) | ↓ |
GM-CSF | 25.00 (0.83-128.05) | 15.31 (3.55–60.26) | ↑ | 4.24 (0.42–23.21) | 2.26 (0.64–5.28) | ↑ |
I-309 | 0.90 (0.24–3.18) | 2.19 (0.24–5.35) | ↓ | 1.14 (0.81–1.92) | 1.01 (0.69–1.25) | ↑ |
GRO-alpha | 8.37 (1.45–44.80) | 3.39 (0.18–22.15) | ↑* | 2.74 (0.98–8.96) | 8.37 (0.79–28.08) | ↓* |
IL-17A-F | 0.48 (0.18–1.48) | 4.17 (0.07–45.26) | ↓ | 0.75 (0.47–1.39) | 0.84 (0.32–1.35) | ↓ |
MIP-5 | 0.01 (0.00-0.04) | 0.01 (0.00-0.04) | ↑ | 20.62 (13.38–37.51) | 21.91 (12.96–34.69) | ↓ |
MCP-2 | 0.16 (0.06–0.30) | 0.19 (0.11–0.36) | ↓ | 3.13 (1.58–6.55) | 2.95 (2.14–3.95) | ↑ |
Fractalkine | 0.33 (0.07–0.97) | 0.18 (0.04–0.38) | ↑ | 3.90 (2.25–5.67) | 3.91 (2.10–8.37) | ↓ |
IL-6 | 3.00 (0.15–21.23) | 2.21 (0.11–10.40) | ↑ | 1.47 (0.42–2.85) | 0.74 (0.09–2.71) | ↑* |