The inflammatory profile of cerebrospinal fluid, plasma, and saliva from patients with severe neuropathic pain and healthy controls-a pilot study

Table 4 Proteins important for OPLS regression of VASPI in patients

Cytokine/chemokine	Biofluid	VIP	p(corr)
IL-17D	Plasma	1.69	− 0.95
IL-17F	Plasma	1.61	− 0.92
IL-3	Plasma	1.55	− 0.87
IL-17E-IL-25	Plasma	1.5	− 0.85
IL-31	Plasma	1.51	− 0.85
IL-17B	Plasma	1.51	− 0.84
IL-23	Plasma	1.47	− 0.83
IL-33	Plasma	1.44	− 0.81
ENA-78	Plasma	1.34	− 0.72
VEGF-A	Plasma	1.26	− 0.70
IL-7	Plasma	1.28	− 0.68
GM-CSF	Plasma	1.19	− 0.67
MCP-2	Saliva	1.01	− 0.60
Fractalkine	Plasma	1.02	− 0.57
IL-6	CSF	1.01	0.56
MIP-5	Plasma	1.06	0.60
IL-17A-F	Plasma	1.08	0.62

Proteins are presented in descending order of importance with respect to absolute p(corr) of the first latent (predictive) variable. A positive p(corr) signifies a positive association with VASPI, and a negative p(corr) signifies the opposite

ISSN: 1471-2202