Fig. 6

The presence of Q-VD-OPH, in both male and female-derived slices, in combination with either progesterone or estradiol significantly increased (*P < 0.01) the amount of cell death seen in comparison to progesterone or estradiol only in both CA1 and DG regions (a, b). The addition of PJ-34, in both male and female-derived slices, in combination with either progesterone or estradiol significantly increased (*P < 0.01) the amount of cell death seen in comparison to progesterone or estradiol only in both CA1 and DG regions (c, d). PROG: progesterone, E2: estradiol; data are expressed as mean ± SEM and n = 8 independent wells