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Table 4 Summary of Rostro-Caudal patterns of aromatase control of ventromedial hypothalamic nucleus (VMN) metabolic transmitter, glycogen metabolic, and pyruvate recycling pathway enzyme protein expression in eu- and hypoglycemic male versus female rats

From: Sex-dimorphic neuroestradiol regulation of ventromedial hypothalamic nucleus glucoregulatory transmitter and glycogen metabolism enzyme protein expression in the rat

  1. a Intracerebroventricular (icv) vehicle (V) infusion days 5–11; subcutaneous (sc) vehicle (V) injection day 11
  2. b icv V infusion days 5–11; sc 10.0 U neutral protamine Hagedorn insulin (INS)/kg bw injection day 11
  3. c icv letrozole (1.67 μg/μL dosage, 0.5 μL/h infusion rate) infusion days 5–11; sc V injection day 11
  4. d icv letrozole infusion days 5–11; sc INS injection day 11
  5. e V/INS vs V/V
  6. f Lz/V vs V/V
  7. g Lz/INS vs Lz/V
  8. h No change
  9. i Neuronal nitric oxide synthase
  10. j Glutamate decarboxylase 65/67
  11. k Glycogen synthase
  12. l Glycogen phosphorylase-brain type
  13. m Glycogen phosphorylase-muscle type
  14. n Glutaminase
  15. o Malic enzyme-1