Fig. 8

Expression profiles of pyruvate recycling pathway marker protein malic enzyme-1 (ME-1) protein in male versus female rat VMN; Impact of icv Lz infusion. Mean normalized rostral (a; F_(7,40) = 7.21; p < 0.0001), middle (b; F_(7,40) = 5.52; p < 0.0001), and caudal (c; F_(7,40) = 8.14; p < 0.0001) VMN GPbb protein O.D. values ± S.E.M. are presented for V/V, V/INS, Lz/V, and Lz/INS groups of male (M; left-hand side) and female (F; right-hand side) rats; n = 6 animals per group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Results are summarized in the table at bottom; ↑ and ↓ denote a relative increase or decrease, respectively, between treatment groups; no change (NC) between groups is also indicated