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Fig. 3 | BMC Neuroscience

Fig. 3

From: Sex-dimorphic neuroestradiol regulation of ventromedial hypothalamic nucleus glucoregulatory transmitter and glycogen metabolism enzyme protein expression in the rat

Fig. 3

Basal and hypoglycemic patterns of VMN gluco-inhibitory γ-aminobutyric acid (GABA) marker protein expression in icv Lz-pretreated male versus female rats. The GABA transmitter marker protein glutamate decarboxylase65/67 (GAD) was measured in the rostral (a; F(7,40) = 27.15; p < 0.0001), middle (b; F(7,40) = 28.85; p < 0.0001), and caudal (c; F(7,40) = 8.07; p < 0.0001) VMN of V/V, V/INS, Lz/V, and Lz/INS groups of male (M; left-hand side) and female (F; right-hand side) rats. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. For each VMN segment, data depict mean normalized GAD O.D. values ± S.E.M. Results are summarized in the table at bottom; ↑ and ↓ denote a relative increase or decrease, respectively, between treatment groups; no change (NC) between groups is also indicated

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