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Table 1 Nerve regeneration after nerve injury and repair in healthy and diabetic rats

From: Correction to: Gender differences in nerve regeneration after sciatic nerve injury and repair in healthy and in type 2 diabetic Goto-Kakizaki rats

  Healthy
Male
(n = 10)
Healthy
Female
(n = 10)
Diabetes
Male
(n = 10)
Diabetes
Female
(n = 10)
p-values
(KWa)
Fisher’s methodb
Male/
female
Healthy/
Diabetes
Axonal outgrowth (neurofilaments, mm) 7.0
(6.8–7.3)
6.3
(6.1–6.4)
6.9
(6.7–7.1)
5.8
(5.1–6.2)
0.0001  < 0.0001 0.02
ATF-3 (% of total) SNL 17.8
(17.6–18.4)
17.6
(16.7–18.0)
19.8
(19.1–21.1)
16.4
(15.7–17.3)
0.0001 0.0001 0.001
ATF-3 (% of total) SND 19.2
(17.7–19.6)
19.5
(18.9–20.1)
18.7
(16.9–20.1)
15.2
(14.4–15.7)
0.0001 0.0003 0.001
Cleaved caspase-3 (% of total) SNL 5.2
(2.6–7.8)
3.1
(2.9–3.4)
9.6
(8.7–11.6)
7.0
(6.4–10.1)
0.0001 0.31  < 0.0001
Cleaved caspase-3 (% of total) SND 2.7
(2.2–4.0)
2.5
(2.4–2.7)
6.4
(4.5–7.1)
5.8
(4.3–6.1)
0.0001 0.39  < 0.0001
Total cell number (mm2) SNL 5344
(5297–5367)
4935
(4827–5010)
5043
(4916–5184)
5118
(4977–5161)
0.0001 0.0005 0.0001
Total cell number (mm2) SND 5344
(5273–5414)
5226
(5020–5391)
4949
(4789–5128)
5137
(4911–5179)
0.0001 0.07  < 0.0001
Preoperative B-glucose (mmol/l) 4.6
(4.3–4.9)
3.90
(3.8–4.3)
15.0
(13.3–17.2)
10.3
(9.7–11.7)
0.0001  < 0.0001  < 0.0001
Weight increase (%) 2.2
(0.7–2.7)
2.4
(1.3–4.8)
2.0
(1.2–2.6)
2.6
(2.0–3.2)
0.34
  1. Values are median 25th (Q1)−75th (Q3) percentiles. p-values in italics is significantly different at least at the 0.05 level. aKW = Kruskal–Wallis. bFisher method for independent samples based on the chi square distribution. SNL site of lesion, SND distal nerve segment. Total cell = DAPI stained cells