Fig. 1

Example fitting run. Sodium-free saline is washed in (epochs 1-50), and gradually removed (51-100). Left: Voltage of the neuron (red) and best model (blue) in response to a ramp stimulus. Bottom: Spike counts with the same stimulus. Right: Value distributions of some of the fitted parameters (y axis) through time (x axis). The model recapitulates the change in sodium (top 2 plots)