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Fig. 6 | BMC Neuroscience

Fig. 6

From: NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment

Fig. 6

ALA protected IHG-induced cell apoptosis through NGF receptors and the PI3K/AKT pathway in PC12 cells. Bax/Bcl-2 and Caspase-3 levels were evaluated in the presence or absence of K252a (a–c), TAT-pep5 (d-f), and LY294002 (g–i), respectively. Data are shown as the mean ± SD (n = 3). ##P < 0.01, #P < 0.05 versus the IHG group; ++P < 0.01, +P < 0.05 compared to the IHG + ALA group; and *P < 0.05 compared to the IHG + inhibitor (K252a, TAT-pep5, or LY294002)

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BMC Neuroscience

ISSN: 1471-2202

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