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Fig. 3 | BMC Neuroscience

Fig. 3

From: Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants

Fig. 3

Anti-TDP scFvs characterization with FTD and control sera. Reactivity of anti-TDP scFvs with FTD and AD sera were assessed using sandwich ELISA. 4 of the 5 anti-TDP scFvs selectively bind to both FTD-TDP (n = 12) and FTD-tau (n = 12) sera and has relatively little to no binding to AD sera (n = 11). FTDP-TDP5 was the only scFv that had reactivity with FTD-TDP, FTD-Tau and AD sera over cognitively normal healthy controls. Error bars based on SEM

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