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Table 3 Coefficient of variation (CV) for inter-scanner volumetric measurement between each pair of scanners

From: Inter-scanner reproducibility of brain volumetry: influence of automated brain segmentation software

 

Freesurfer

FSL-FIRST

AccuBrain

GE vs. PHILIPS

GE vs. SIEMENS

PHILIPS vs. SIEMENS

GE vs. PHILIPS

GE vs. SIEMENS

PHILIPS vs. SIEMENS

GE vs. PHILIPS

GE vs. SIEMENS

PHILIPS vs. SIEMENS

WM

8.393

0.903

7.874

N.A.

N.A.

N.A.

0.999

0.818

1.138

GM

6.835

1.142

7.223

N.A.

N.A.

N.A.

1.581

1.357

1.376

Hippocampus L

8.165

2.583

6.471

7.802

7.603

7.814

8.810

5.916

6.615

Hippocampus R

8.947

2.062

7.723

8.160

8.431

8.949

6.636

5.958

6.374

Amygdala L

9.192

7.257

7.429

15.23

8.490

18.15

2.029

3.246

3.233

Amygdala R

9.765

2.699

9.996

13.86

13.62

21.76

3.000

1.756

3.385

Lateral ventricle L

7.307

4.174

9.454

N.A.

N.A.

N.A.

2.332

1.352

2.419

Lateral ventricle R

8.131

2.478

8.356

N.A.

N.A.

N.A.

2.684

2.086

2.763

VentralDC L

9.536

2.908

9.250

N.A.

N.A.

N.A.

4.573

4.217

1.268

VentralDC R

9.621

2.952

8.060

N.A.

N.A.

N.A.

3.918

3.222

1.459

Thalamus L

8.538

2.611

7.701

3.052

8.805

8.357

1.569

0.984

1.354

Thalamus R

8.576

2.672

9.367

2.603

9.811

9.126

0.928

1.676

1.676

Caudate L

8.058

4.347

9.700

7.599

12.30

10.25

2.875

1.308

1.627

Caudate R

8.678

2.803

9.218

9.815

11.28

12.37

2.147

1.463

1.727

Putamen L

10.70

4.854

8.713

7.811

13.66

6.006

2.663

2.022

1.788

Putamen R

9.662

3.231

8.733

8.854

13.26

6.034

2.231

2.590

1.499

Pallidum L

9.381

7.032

12.41

5.857

7.079

4.253

4.174

3.178

2.232

Pallidum R

8.093

7.788

11.46

6.331

9.790

6.236

2.158

1.418

1.889

Accumbens L

9.714

7.977

9.544

7.800

10.96

13.44

3.572

3.583

4.223

Accumbens R

8.844

6.046

9.091

16.31

12.92

14.93

4.093

2.793

4.671

Average.

8.807

3.926

8.789

8.650

10.57

10.55

3.149

2.547

2.636

  1. The mean values of region-specific CV (i.e. inter-scanner variability in brain volumetry of GE vs. PHILPS, GE vs. SIEMENS and PHILIPS vs. SIEMENS) of the examined 15 subjects are displayed for each ABS tool
  2. GM gray matter, N.A: not available, WM white matter, VentralDC ventral diencephalon, L Left, R Right
  3. The average CV of FSL-FIRST for different brain substructures is the mean over the structures available for quantification in FSL-FIRST (i.e. hippocampus, amygdala, thalamus, caudate, putamen, pallidum and accumbens)