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Table 1 Results of the post hoc tests for rs11787922 (the original test is included as a point of reference)

From: Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study

Test Description of the test Test statistic Effect of T allele on TROG-2 score, where relevant P value
Original test from the paternal parent-of-origin discovery analysis This test compares two models, where only the full model includes the effect of only paternally-derived alleles. The likelihoods of the two models are then compared using a likelihood ratio test (χ2 statistic). χ2 = 32.76; df = 1 − 23.05 1.04 × 10−8
Test for the difference between paternal and maternal alleles This test compares two models, where the null model already has the X = within = between family component from the “total” association model, and the full model includes, in addition to X, the effect of only maternally-derived alleles. The likelihoods of the two models are then compared using a likelihood ratio test (χ2 statistic). χ2 = 20.7; df = 1   5 × 10−6
Paternal parent-of-origin test with covariates for ASD, ADHD, and index family status This test compares two models, where only the full model includes the effect of only paternally-derived alleles. Both models include the effects of the covariates. The likelihoods of the two models are then compared using a likelihood ratio test (χ2 statistic). χ2 = 30.55; df = 1 − 21.3 3.25 × 10−8
Paternal parent-of-origin test with a covariate for sex This test compares two models, where only the full model includes the effect of only paternally-derived alleles. Both models include the effect of the covariate. The likelihoods of the two models are then compared using a likelihood ratio test (χ2 statistic). χ2 = 32.61; df = 1 − 22.9 1.13 × 10−8
Paternal parent-of-origin test using Z-scores of the transformed TROG-2 scores This test compares two models, where only the full model includes the effect of only paternally-derived alleles. The likelihoods of the two models are then compared using a likelihood ratio test (χ2 statistic). χ2 = 24.28; df = 1   8.33 × 10−7
A test for the presence of a parent-of-origin effect in unrelated individuals This test compares the trait variance of the heterozygous group to those of the homozygous groups. \(\frac{{\hat{b}}}{{SE_{b} }}\;\sim \;N\;\left( {0,1} \right) \; = \;0. 2 6 6 4/0.0 8 9 8\)   0.0016