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Fig. 2 | BMC Neuroscience

Fig. 2

From: Resuscitation with macromolecular superoxide dismutase/catalase mimetic polynitroxylated PEGylated hemoglobin offers neuroprotection in guinea pigs after traumatic brain injury combined with hemorrhage shock

Fig. 2

Accumulated shed blood and mean arterial blood pressure. a Time course of blood withdrawn after TBI for the two groups that were subsequently resuscitated with lactated Ringer’s (LR) or PNPH (mean ± SD; n = 12). Because blood withdrawal was stopped temporarily when mean arterial pressure declined to below 35–40 mmHg, the rate of hemorrhage differed among guinea pigs, but the average rate did not differ between the LR and PNPH groups. b Mean arterial pressure in guinea pigs subjected to sham operation (n = 6) or TBI at time 0, during hemorrhage (20–90 min), and during fluid resuscitation with either LR or PNPH (90–180 min). *P < 0.05 versus both TBI + hemorrhagic shock (HS) groups; +P < 0.05 versus sham and LR resuscitation groups

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BMC Neuroscience

ISSN: 1471-2202

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