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Fig. 6 | BMC Neuroscience

Fig. 6

From: The role of PI3K-mediated AMPA receptor changes in post-conditioning of propofol in brain protection

Fig. 6

The expression of pGluR2 during post-conditioning induced by propofol. A The phosphorylation level of GluR2 after propofol post-conditioning. The tissue from Ischemic hippocampus was incubated with anti-pGluR2 antibody (S880) and concentration of pGluR2 was detected by Western Blot (100 kDa). S: sham-operated group; IR: P: propofol Post-cond group; L + S: sham-operated group; L + IR: LY294002 + ischemia–reperfusion injury group; L + P:LY294002 + propofol Post-cond group. B Compared with Group S, the injury brain would express more pGluR2;when compared with Group IR, it was at lower level in Group P; More noteworthy is that inhibitor of PI3K could up-regulate the level which was reduced by propofol. n = 6 for each group. **P < 0.01 vs Group IR; #P < 0.05 vs Group P; ##P < 0.05 vs Group P

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