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Fig. 5 | BMC Neuroscience

Fig. 5

From: The involvement of spinal annexin A10/NF-κB/MMP-9 pathway in the development of neuropathic pain in rats

Fig. 5

Effects of NFκB inhibitor (PDTC) on the expression of spinal MMP9 and proinflammatory cytokines. a Western blot analysis of the expression of spinal ANXA10, pNF-κB, MMP9 on day 1 and day 7 after surgery in SNL + DMSO, and SNL + PDTC group. The DMSO or PDTC was administrated on day 1 before surgery, at 2 h before surgery, on day 1 after surgery. Fold change for the density of protein level was normalized to GAPDH. (&&p < 0.01, &&&p < 0.001, compared with “SNL + DMSO” group, n = 4) b ELISA analysis of the expression of spinal TNF-α, IL-1β, and IL-6 in SNL + DMSO, and SNL + PDTC group. ($ p < 0.05, $$p < 0.01, $$$ p < 0.001 compared with “SNL + DMSO” group, n = 4)

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