Fig. 1

Effects of mul1 and park mutations on lifespan and the circadian rhythm of locomotor activity. a Kaplan–Meier survival curve. Dead flies were counted every 3 days. Statistically significant differences were detected between white control and mul1 (p < 0.05), and also between white and park mutants (p < 0.05). N of w¹¹¹⁸ = 231, N of park¹ = 150, N of mul1^A6 = 233. b Total activity and sleep duration during the day and at night in LD 12:12. The Y-axis shows time in minutes when flies were active or their sleep time (means ± SD) (four asterisks indicates p < 0.01). N of w¹¹¹⁸ = 25, N of park¹ = 29, N of mul1^A6 = 21. c Period of locomotor activity rhythm in all studied genotypes (means ± SD). Statistically significant differences were detected between white control and mul1 (p < 0.05), and also between white and park mutants (p < 0.05). N of w¹¹¹⁸ = 31, N of park¹ = 47, N of mul1^A6 = 45