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Fig. 9 | BMC Neuroscience

Fig. 9

From: Involvement of brain-derived neurotrophic factor (BDNF) in chronic intermittent stress-induced enhanced mechanical allodynia in a rat model of burn pain

Fig. 9

Effects of CTX-B on PFC and hypothalamic TrkB and p-TrkB levels in stressed rats with thermal injury. p-TrkB and TrkB protein levels in the ipsilateral and contralateral PFC and hypothalamus of NS, S + I + Saline and S + I + CTX-B treated rats are shown by Simple Western blot representative image (above quantification graphs of ad). TrkB and p-TrkB levels in the ipsilateral and contralateral PFC were comparable between all groups (a, b). CTX-B treatment in the S + I group significantly reduced hypothalamic TrkB and p-TrkB levels compared to the S + I + Saline group (c, d). NS non-stress, S stress, I injury; CTX-B cyclotraxin-B, Sal saline. n = 5/group. * = P < 0.05 and ** = P < 0.01

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