Fig. 5

Anxiety-like behavior and locomotor activity in the open field (OF). Bar graphs show the results of the OF test. B7-H1 ko and wildtype littermates (WT) were investigated naïve, after chronic constriction injury (CCI), and sham surgery. No difference was found between genotypes and surgeries in the number of entries into the center zone (a). b B7-H1 ko mice travelled more after CCI compared to WT mice (p < 0.05). WT mice travelled less after CCI compared to sham surgery (p < 0.05). c No difference in time travelled in the center zone was detected. d Total distance travelled did not differ between genotypes and surgeries. B7-H1 ko: sham: 14 males, CCI: 22 males. WT: sham: 11 males, CCI: 20 males. *p < 0.05