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Table 3 Phenotypic differences observed between TPS and LDPT neurons

From: Effect of lesion proximity on the regenerative response of long descending propriospinal neurons after spinal transection injury

Gene

LDPT

TPS

Fold change

P value

Grouping

Observed phenotypic differences

 Actb

8501.71

6179.14

0.73

0.0421

RAG

 Atf3

9.18

12.08

1.32

0.4635

RAG

 Bdnf

20.63

31.57

1.53

0.3192

SRGF

 Casp2

4.90

12.04

2.46

0.0032

AP

 Casp3

147.00

90.46

0.62

0.2382

AP

 Cybb

1.53

6.05

3.95

0.2659

IM

 Dap

29.34

66.94

2.28

0.0159

AP

 Fcgr2b

6.62

39.48

5.97

0.0377

IM

 Fyb

5.58

16.82

3.02

0.1329

IM

 Gadd45a

284.22

196.00

0.69

0.0063

RAG

 Gadd45g

5.18

9.66

1.87

0.0616

AP

 Gap43

1087.25

1300.25

1.20

0.0413

RAG

 Gfra1

83.58

112.05

1.34

0.1237

SRGF

 Hsbp1

1739.43

1436.72

0.83

0.0728

RAG

 Igf1

5.51

9.68

1.76

0.0121

SRGF

 Itgam

23.87

79.00

3.31

0.0016

IM

 Jun

119.38

113.87

0.95

0.8782

RAG

 Lgals3

13.68

354.43

25.92

0.2606

IM

 Lifr

461.73

334.60

0.72

0.0158

SRGF

 Ncam1

854.72

803.53

0.94

0.7075

SRGF

 Ntrk2

97.77

94.62

0.97

0.9017

SRGF

 Pycard

2.42

10.06

4.15

0.0035

AP

 Ret

444.09

330.41

0.74

0.0754

SRGF

 Sox11

1.36

4.22

3.10

0.2533

RAG

 Stat3

320.89

327.53

1.02

0.8987

RAG

 Stmn2

3837.24

2345.47

0.61

0.0333

RAG

 Tbp

35.70

47.64

1.33

0.1195

RAG

 Tspo

5.74

37.08

6.46

0.0023

RAG

 Tubb3

1588.09

1060.08

0.67

0.0353

RAG

  1. Phenotypic differences between TPS and LDPT Neurons. Phenotypic differences were detected utilizing a T test that compared the  baseline expression level of the genes of interest in uninjured LDPT and TPS neurons. Significant p values are shown in italics
  2. The “family” that each gene was assigned to is indicated in the far right column AP pro/anti apoptotic genes, IM immune and inflammatory, RAG regeneration associated and/or neuroprotective genes; SRGF surface receptor and/or growth factor