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Fig. 5 | BMC Neuroscience

Fig. 5

From: Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease

Fig. 5

Fluorescence intensity of Aβ1-42 is increased in Chlamydia pneumoniae-infected astrocytes. Aβ1-42 (red) and Cpn (green) were visualized by laser scanning, confocal microscopy (a). To analyze the Z-images using FIJI software, a defined threshold subtraction was applied equally to each image to determine Aβ1-42 fluorescence intensity (b); mean fluorescence intensity was calculated for infected and uninfected astrocytes at 24, 48 and 72 hpi. Cells (N = 25–30) were analyzed across three biological replicates to reliably conduct a student’s t-test on the fluorescence intensities of Aβ1-2 in uninfected and Cpn-infected cells. Error bars represent standard error of the mean. Asterisk represents p < 0.05

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BMC Neuroscience

ISSN: 1471-2202

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