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Table 2 Significant clusters of deactivation before the exercise stressors

From: Exercise challenge alters Default Mode Network dynamics in Gulf War Illness

Pre-exercise fMRI
Group Cluster Size T-score peak voxel MNI Coordinates*
Controls (n = 10)
Bilateral dorsomedial prefrontal cortex 769 9.07 4, 44, 52
− 10, 50, 38
− 6, 40, 56
Left ventromedial prefrontal cortex 161 6.25 − 8, 50, − 14
− 2, 54, 4
− 10, 54, − 6
STOPP subjects (n = 18)
Bilateral dorsomedial prefrontal cortex 1413 6.11 − 2, 60, 12
4, 52, 44
− 6, 62, 22
START subjects (n = 10)
Right ventromedial prefrontal cortex 323 7.57 10, 54, 42
8, 54, 28
  1. Prior to exercise, controls and GWI groups deactivated similar regions within the medial prefrontal cortex
  2. * Greater than 1 reported MNI coordinate shows separate (> 8 mm apart) local maxima within a cluster. (P < 0.05, clusterwise corrected threshold; MNI coordinates x, y and z in mm)