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Fig. 3 | BMC Neuroscience

Fig. 3

From: Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla 1H-MRS study

Fig. 3

Glu and NAA changes after TBI. a The Glu/Cr ratios in the ipsilateral side in both KO + CCI mice and WT + CCI mice were significantly lower than those in the KO + sham and WT + sham mice. This ratio was also significantly lower than that in each contralateral side (*p < 0.05). Moreover, the reduction in Glu/Cr ratio was less marked in GCP II-KO mice than in WT mice (#p < 0.05). b The NAA/Cr ratio of the ipsilateral hippocampus in GCP II-KO mice was significantly lower than that of the contralateral side and the two sham CCI groups (*p < 0.05). A similar result was found within the ipsilateral hippocampus in WT mice (*p < 0.05), as compared with the contralateral side and the two sham CCI groups. In addition, the reduction in NAA/Cr ratio was less marked in GCP II-KO mice than in WT mice. (#p < 0.05)

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BMC Neuroscience

ISSN: 1471-2202

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