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Table 1 Patients with and without anti-neuronal antibodies were compared on the following clinical characteristics

From: The significance of anti-neuronal antibodies for acute psychiatric disorders: a retrospective case–controlled study

Clinical characteristic

NMDAR

CASPR2

GAD65

Variable

Obtained

Definitions

Hallucinations

X

X

n/a

Dichotome (Yes/No)

Retrospective

Vis., aud., tact. and/or olf.

Delusions

X

X

n/a

Dichotome (Yes/No)

Retrospective

Described in chart

Lowered mood

X

X

X

Dichotome (Yes/No)

Retrospective

Described in chart

Elevated mood

X

n/a

n/a

Dichotome (Yes/No)

Retrospective

Described in chart

Irritability

X

n/a

X

Dichotome (Yes/No)

Prospective

Brøset Violence Checklist

Disorientation

X

X

X

Dichotome (Yes/No)

Prospective

Brøset Violence Checklist

Disinhibition

X

n/a

n/a

Continuous (1–7)

Prospective

PANSS Item G14

Agitation

X

X

X

Continuous (5–35)

Prospective

PANSS-EC

Symptom fluctuation

X

n/a

n/a

Continuous (1–10)

Prospective

SOMAS Item A

Total sleep time (actigraphy)

X

X

n/a

Continuous (min)

Prospective

According to actigraphy software algorithms

Wake after sleep onset (actigraphy)

X

X

n/a

Continuous (min)

Prospective

According to actigraphy software algorithms

  1. aud auditive, CASPR2 contactin-associated protein 2, GAD65 glutamic acid decarboxylase 65, n/a not applicable (because the systematic literature search did not reveal associations between the symptom variable and the specific antibody), NMDAR N-methyl-d-aspartate receptor, olf olfactory, PANSS positive and negative syndrome scale, PANSS-EC positive and negative syndrome scale- excited component, SOMAS Symptomatic Organic Mental Disorder Assessment Scale, tact tactile, Vis visual